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Biological Research For Nursing
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Basic Concepts of Optical Mapping Techniques in Cardiac Electrophysiology

Mina Attin, RN, PhD

From the College of Nursing, University of Illinois at Chicago, Illinois, minaattin{at}aol.com

William T. Clusin, MD, PhD

(MA); and Cardiovascular Division, Stanford University School of Medicine, California

Optical mapping is a tool used in cardiac electrophysiology to study the heart’s normal rhythm and arrhythmias. The optical mapping technique provides a unique opportunity to obtain membrane potential recordings with a higher temporal and spatial resolution than electrical mapping. Additionally, it allows simultaneous recording of membrane potential and calcium transients in the whole heart. This article presents the basic concepts of optical mapping techniques as an introduction for students and investigators in experimental laboratories unfamiliar with it.

Key Words: optical mapping • cardiac electrophysiology • ventricular arrhythmias

This version was published on October 1, 2009

Biological Research For Nursing, Vol. 11, No. 2, 195-207 (2009)
DOI: 10.1177/1099800409338516
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