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Biological Research For Nursing, Vol. 2, No. 1, 41-48 (2000)
DOI: 10.1177/109980040000200105

Understanding Cytokines Part II: Implications for Nursing Research and Practice

Elizabeth J. Corwin, PhD, MSN, CRNP

School of Nursing and the Intercollege Physiology Program, Pennsylvania State University.

Cytokines are small signaling proteins released from a variety of cells that influence virtually every aspect of growth and development and every host response to infection, injury, and inflammation. Because of their widespread and potent effects across the life span, cytokines without a doubt influence nursing research and practice. From physiological and adaptive effects of cytokines to cytokine-induced diseases, nurses and nursing care are involved. Part II of this review highlights a few of the many examples of cytokines functioning in response to infection and inflammation, during the processes of reproduction, and in a variety of pathophysiological states. Implications for nursing research and practice are emphasized.

Key Words: Cytokines • immune system • autoimmune disease • sickness behavior


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