This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Reddy, B. K. Articles by Cooper, C. J. Search for Related Content PubMed PubMed Citation Articles by Reddy, B. K. Articles by Cooper, C. J. Social Bookmarking                   What's this?

Compliance with Antihypertensive Therapy after Renal Artery Stenting

David J. Kennedy, MS

William R. Colyer, MD

Mark W. Burket, MD

William J. Thomas, MD

Sadik A. Khuder, PhD

Joseph I. Shapiro, MD

Department of Medicine, at the Medical College of Ohio, Toledo

Robert V. Topp, RN, PhD

School of Nursing at University of Louisville, KY.

Christopher J. Cooper, MD

Division of Cardiology, Medical College of Ohio, 3000 Arlington Avenue, Toledo, OH 43614-2598 ccooper{at}mco.edu

Hypertension is an important clinical endpoint after renal artery revascularization for renal artery stenosis (RAS). Medication compliance is a critical determinant of blood pressure control. Although factors influencing compliance are known in essential hypertension, they have not been evaluated in studies investigating renal artery revascularization. The aim of this study was to assess the determinants of compliance to antihypertensive therapy in patients with RAS following renal artery stent placement (RASP). A cross-sectional study evaluating blood pressure, antihypertensive medications, quality of life, compliance, and determinants of compliance to antihypertensive therapy was undertaken in 112 patients undergoing RASP. Additionally, cardiovascular risk factors, antihypertensive medications, and cardiovascular history were reported. Self-reported compliance was 79% ± 24% (scale of 0% [none] to 100% [complete] compliance) in patients after RASP. Determinants of compliance by multivariate analysis included physical symptoms, which correlated negatively to compliance and included loss of appetite (r² = 0.26, P < 0.0001), dizziness (r² = 0.06, P < 0.01), and cough (r² = 0.03, P < 0.05). Systolic blood pressure correlated positively with compliance (r² = 0.03, P < 0.05). The number or class of antihypertensive medications did not influence compliance. Patients' physical symptoms and level of systolic blood pressure, rather than the number or class of medications, influence compliance in patients with continued hypertension after RASP. Attention to physical symptoms may help to improve blood pressure control in this population.

Key Words: compliance • antihypertensive therapy • renal artery stenosis • renal artery stenting

Biological Research For Nursing, Vol. 5, No. 1, 37-46 (2003)
DOI: 10.1177/1099800403005001004


CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				D. J. Kennedy, M. W. Burket, S. A. Khuder, J. I. Shapiro, R. V. Topp, and C. J. Cooper Quality of life improves after renal artery stenting. Biol Res Nurs, October 1, 2006; 8(2): 129 - 137. [Abstract] [PDF]