| Sign In to gain access to subscriptions and/or personal tools. |
DOI: 10.1177/1099800407311016 © 2008 SAGE Publications Sleep Disorders, Glucose Regulation, and Type 2 DiabetesUniversity of Medicine and Dentistry of New Jersey School of Nursing, Newark, New Jersey , taublm{at}umdnj.edu
Yale University School of Nursing, New Haven, Connecticut Recent epidemiological, biological, and behavioral evidence suggests that sleep disorders may contribute to the development of diabetes; conversely, diabetes itself may contribute to sleep disorders. Sleep appears to moderate the neurohormones that regulate blood glucose. Sleep deprivation and sleep disorders contribute to pathophysiological changes associated with the development of type 2 diabetes. In people who already have diabetes, sleep deprivation contributes to elevations of hemoglobin A1c. Symptoms that occur as a result of diabetes, such as nocturia and neuropathic pain, may in turn contribute to sleep disturbance and exacerbate sleep deprivation. The purposes of this article are to examine the scientific basis for the associations between diabetes and sleep, identify gaps in the understanding of the empirical underpinnings of these relationships, and propose directions for future research.
Key Words: diabetes sleep sleep apnea insulin resistance circadian rhythm inflammatory markers
|